1001565-97-4Relevant academic research and scientific papers
Convergent and Biomimetic Enantioselective Total Synthesis of (-)-Communesin F
Lathrop, Stephen P.,Pompeo, Matthew,Chang, Wen-Tau T.,Movassaghi, Mohammad
, p. 7763 - 7769 (2016)
The first biomimetic enantioselective total synthesis of (-)-communesin F based on a late-stage heterodimerization and aminal exchange is described. Our synthesis features the expedient diazene-directed assembly of two advanced fragments to secure the con
Electrochemical synthesis of 3a-bromofuranoindolines and 3a-bromopyrroloindolines mediated by MgBr2
Wu, Ju,Abou-Hamdan, Hussein,Guillot, Régis,Kouklovsky, Cyrille,Vincent, Guillaume
, p. 1713 - 1716 (2020)
We report an efficient and environmentally friendly electrochemical approach to perform the bromo cyclization of tryptophol, tryptamine and tryptophan derivatives. The 3a-bromofuranoindolines and 3a-bromopyrroloindolines obtained are of interest in the to
CONVERGENT AND ENANTIOSELECTIVE TOTAL SYNTHESIS OF COMMUNESIN ANALOGS
-
Paragraph 00143, (2017/12/02)
A highly convergent biomimetic synthesis of a complex polycyclic scaffold has been successfully implemented. From these efforts, compounds having a structure of Formula (I) or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R
Mechanistic insights into the stereocontrolled synthesis of hexahydropyrrolo[2,3-b]indoles by electrophilic activation of tryptophan derivatives
Lopez, Carlos Silva,Perez-Balado, Carlos,Rodriguez-Grana, Paula,De Lera, Angel R.
, p. 77 - 80 (2008/09/17)
A three-step mechanism involving the formation and rearrangement of an intermediate with indoline-azetidine spirocyclic core structure was shown by DFT computations to account for the electrophilic cyclization of tryptophan derivatives to hexahydropyrrolo
