1001635-30-8

Basic information

• Product Name: 3-Amino-5-methylpyridine-2-carbonitrile
• Synonyms: 3-Amino-5-methylpyridine-2-carbonitrile;3-AMino-2-cyano-5-Methylpyridine;3-Amino-5-methylpicolinonitrile, 3-Amino-2-cyano-5-methylpyridine;3-aMino-5-Methylpyridin-2-carbonitrile;3-aMino-5-Methylpicolinonitrile;2-Pyridinecarbonitrile,3-aMino-5-Methyl-;3-amino-5-methyl-2-Pyridinecarbonitrile
• CAS NO: 1001635-30-8
• Molecular Formula: C₇H₇N₃
• Molecular Weight: 133
• Product Categories: Heterocycle-Pyridine series
• Mol File: 1001635-30-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 370.3±42.0 °C(Predicted)
• Appearance: /
• Density: 1.18
• Storage Temp.: 2-8°C(protect from light)
• PKA: 0.91±0.20(Predicted)
• CAS DataBase Reference: 3-Amino-5-methylpyridine-2-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Amino-5-methylpyridine-2-carbonitrile(1001635-30-8)
• EPA Substance Registry System: 3-Amino-5-methylpyridine-2-carbonitrile(1001635-30-8)

Safety Data

• Statements: 25
• Safety Statements: 45
• Hazardous Substances Data: 1001635-30-8(Hazardous Substances Data)

Usage

Uses

3-Amino-2-cyano-5-methylpyridine is a versatile reactant used in the preparation of new series of orally bioavailable chemokine receptor 9 (CCR9) antagonists with potential use for treatment of inflammatory bowel disease.

InChI:InChI=1S/C7H7N3/c1-5-2-6(9)7(3-8)10-4-5/h2,4H,9H2,1H3

Upstream product

• 557-21-1 zinc(II) cyanide 
• 34552-13-1 3-Amino-2-chloro-5-methylpyridine 
• 1089330-68-6 2-cyano-5-methyl-3-nitropyridine 

Downstream Products

• 1100318-71-5 C₁₄H₉ClF₃N₃O₂S 

Relevant articles and documents

Trisubstituted pyrido[2,3-D]pyrimidines, methods for preparing same and therapeutic uses thereof

The present invention relates to compounds of the following general formula (I): wherein: R1 is notably a group —NRaRb, Ra and Rb forming together with the nitrogen atom onto which they are bound, a h

FUSED HETEROARYL PYRIDYL AND PHENYL BENZENESUFLONAMIDES AS CCR2 MODULATORS FOR THE TREAMENT OF INFLAMMATION

Compounds are provided that act as potent antagonists of the CCR2 receptor. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2- mediated diseases and as controls in assays for the identification of CCR2 antagonists. A compound of the formula (I) or a salt thereof: where: R1 and R2 are each independently hydrogen, halogen, C1-8alkyl, -CN. or C1-8 haloalkyl, provided that at least one of R11or R2 is other than hydrogen; each R3 is independently hydrogen; R4 is hydrogen; R5 is halogen or C1-8 alkyl; R6 is hydrogen; X1 is CR7, N or NO; X2 and X4 are N or NO; X3 is CR7; X6 and X7 are each independently selected from CR7, N, and NO; each R7 is independently selected from the group consisting of hydrogen, halogen, substituted or unsubstituted C2-8 alkyl, substituted or unsubstituted C2-8 alkeπyl, substituted or unsubstituted C2-8 alkynyl, -CN. =O, -NO2, -OR6, -OC(O)R8, -CO2R8, -C(O)R8, -C(O)NR0R8, -OC(O)NR9R8, -NR10C(O)R8, -NR10C(O)NR9R8, -NR9R8, -NR10CO2R8, -SR8, -S(O)R8, -S(O)2R8, -S(O)2NR9R8, -NR10S(O)2R8, substituted or unsubstituted C6-10 aryl, substituted or unsubstituted 5- to 10-membered heteroaryl and substituted or unsubstituted 3- to 10-membered heterocyclyl;