1001735-55-2Relevant articles and documents
Solvent-free synthesis of spiro[3H-indole-3,2′-thiazolidines]
Dandia, Anshu,Singh, Ruby,Arya, Kapil
, p. 401 - 408 (2003)
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Synthesis of a New Series of N-Mannich Bases and Polyhydroxy Mannich Bases of Pharmaceutical Interest Related to Isatin and Its Schiff Bases
Afsah, Elsayed M.,Fadda, Ahmad A.,Hanash, Ahlam H.
, p. 736 - 742 (2018/03/21)
The reaction of isatin 1 with benzaldehyde and a sec-amine or the appropriate aldimine afforded the N-Mannich bases 2–3 and the bis-base 4. Treatment of 1 with glutaric dialdehyde and morpholine gave the bis-base 5. Mannich reaction of the Schiff bases 6a–f derived from 1, led to the new Mannich bases and bis-bases 7–9. The use of N-methyl-D-glucamine as the amine component in the Mannich reaction with 6b–f led to the polyhydroxy Mannich bases 11–13.
A facile synthesis of novel spiro-[indole-pyrazolinyl-thiazolidine]-2,4′-dione
Jain, Subhash C.,Sinha, Juhi,Bhagat, Sunita,Errington,Olsen, Carl E.
, p. 563 - 577 (2007/10/03)
A reaction of appropriate indol-2,3-diones with 4-aminoantipyrine has resulted in the formation of hitherto unknown 3-(2,3-dimethyl-5-oxol-phenyl-3-pyrazolin-4-yl-imino)-indol-2- ones in quantitative yields which upon cyclocondensation with mercaptoacetic acid afforded a series of new spiro heterocycles 3'-(2,3-dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl) spiro[3H-indol-3,2'-thiazolidine]-2,4'-diones.