100188-75-8

Upstream product

• 100188-74-7 3-phenyl-9,10-dihydro-1,2-diazaphenanthrene 
• 73594-38-4 9-phenyl-5,6-benzo-1,10-diazatricyclo<5.3.0.0^2,7>deca-5,9-diene 
• 100188-73-6 4-(2-Diazo-2-phenyl-ethyl)-1,2-dihydro-naphthalene 
• 73594-41-9 α-(1,2-benzo-1,3-cyclohexadien-3-yl)acetophenone N-tosylhydrazone 
• 16216-08-3 2-(naphthalen-1-yl)-1-phenylethan-1-one 

Relevant academic research and scientific papers

Copper-Catalyzed Aerobic Annulation of Hydrazones: Direct Access to Cinnolines

A novel method was developed for the construction of biologically active poly-substituted cinnolines from easily accessible hydrazones in good to excellent yields. A simple copper catalyst could efficiently promote C?N bond formation through selective C?H functionalization and dehydrogenative amination. Furthermore, the inert C?Heteroatom (O/F/N) bonds are susceptible to cleavage in high selectivity in the newly developed aerobic annulation, in preference to the alternative C?H bond, which is left intact. (Figure presented.).