1001907-59-0

Basic information

• Product Name: 1-METHYLINDAZOL-7-BORONIC ACID
• Synonyms: 1-METHYLINDAZOL-7-BORONIC ACID;1-METHYL-1H-INDAZOL-7-YLBORONIC ACID;1-METHYL-1H-INDAZOLE-7-BORONIC ACID;7-BORONIC ACID-1-METHYL-1H-INDAZOLE;1-Methyl-1H-indazol-7-boronic acid;1-methyl-1H-indazol-7-yl-7-boronic acid;7-Borono-1-methyl-1H-indazole;1-Methyl-1H-indazol-7-yl-7-ylboronic acid
• CAS NO: 1001907-59-0
• Molecular Formula: C8H9BN2O2
• Molecular Weight: 175.98026
• Product Categories: Indazole;Organoborons
• Mol File: 1001907-59-0.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 397.5 °C at 760 mmHg
• Flash Point: 194.2 °C
• Appearance: /
• Density: 1.27 g/cm³
• Storage Temp.: 2-8°C
• PKA: 8.51±0.30(Predicted)
• CAS DataBase Reference: 1-METHYLINDAZOL-7-BORONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 1-METHYLINDAZOL-7-BORONIC ACID(1001907-59-0)
• EPA Substance Registry System: 1-METHYLINDAZOL-7-BORONIC ACID(1001907-59-0)

Safety Data

• Hazardous Substances Data: 1001907-59-0(Hazardous Substances Data)

Usage

Description

1-METHYLINDAZOL-7-BORONIC ACID is a chemical compound and organoboron reagent that features a boronic acid functional group. It is characterized by an indazole ring with a methyl group at the first position and a boronic acid group at the seventh position. This unique structure and reactivity make it a valuable tool in the development of new organic compounds and drugs, particularly in the fields of organic synthesis and pharmaceutical research.

Uses

Used in Organic Synthesis:
1-METHYLINDAZOL-7-BORONIC ACID is used as a building block for the creation of various organic molecules. Its boronic acid functional group allows for versatile reactions, such as Suzuki-Miyaura cross-coupling, which is widely used for the formation of carbon-carbon bonds. This makes it a valuable component in the synthesis of complex organic molecules.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 1-METHYLINDAZOL-7-BORONIC ACID is used as a key intermediate in the development of new drugs. Its unique structure and reactivity enable the design and synthesis of bioactive molecules with potential therapeutic applications. The indazole core is a common structural motif in various drug candidates, and the boronic acid group can be further functionalized to enhance the pharmacological properties of the resulting compounds.
Used in Drug Design and Development:
1-METHYLINDAZOL-7-BORONIC ACID is employed as a starting material for the design and development of novel drugs. Its reactivity and structural features can be exploited to create molecules with improved potency, selectivity, and pharmacokinetic properties. The boronic acid group can be used to modulate the binding affinity and selectivity of the resulting drug candidates, making it a versatile building block in drug discovery efforts.
Used in Chemical Biology Research:
1-METHYLINDAZOL-7-BORONIC ACID is also used in chemical biology research to study the interactions between small molecules and biological targets. Its reactivity and structural features can be used to probe the binding sites of proteins, enzymes, and other biomolecules, providing insights into the molecular mechanisms of biological processes and the development of targeted therapies.