100201-03-4Relevant academic research and scientific papers
4-NITROPYROCATECHOL ETHERS AS POSSIBLE PHOTOAFFINITY LABELS. PHOTOCHEMICAL REACTIONS OF 4-NITROPYROCATECHOL ETHERS OF BIOLOGICALLY ACTIVE COMPOUNDS
Castello, A.,Cervello, J.,Marquet, J.,Moreno-Manas, M.,Sirera, X.
, p. 4073 - 4082 (2007/10/02)
The photochemical reactions of O- and N-(2-methoxy-4-nitro)phenoxyalkyl derivatives of estrone and of the antibiotic cycloheximide with methylamine afford clean substitutions of the methoxy group.From these experiments it is inferred that 2-methoxy-4-nitrophenyl ethers can be good photoaffinity labels.
THE NUCLEOPHILIC AROMATIC PHOTOSUBSTITUTION IN PHOTOAFFINITY LABELLING. A MODEL STUDY OF A CYCLOHEXIMIDE DERIVATIVE.
Castello, A.,Marquet, J.,Moreno-Manas, M.,Sirera, X.
, p. 2489 - 2492 (2007/10/02)
The photoreactions of several 4-nitrocatechol ethers with the relatively hard nucleophile methylamine occurs at the meta position respect to the nitro group.A derivative of the antibiotic cycloheximide carrying a 4-nitrocatechol ether moiety reacts with methylamine affording an in vitro model for photoaffinity labelling.
