1002107-32-5

Basic information

• Product Name: 1-(4-chlorophenyl)-2-methyl-1H-imidazole-5-carbaldehyde
• Synonyms: 1-(4-chlorophenyl)-2-methyl-1H-imidazole-5-carbaldehyde
• CAS NO: 1002107-32-5
• Molecular Weight: 220.658
• Mol File: 1002107-32-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(4-chlorophenyl)-2-methyl-1H-imidazole-5-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-chlorophenyl)-2-methyl-1H-imidazole-5-carbaldehyde(1002107-32-5)
• EPA Substance Registry System: 1-(4-chlorophenyl)-2-methyl-1H-imidazole-5-carbaldehyde(1002107-32-5)

Safety Data

• Hazardous Substances Data: 1002107-32-5(Hazardous Substances Data)

Upstream product

• 14277-03-3 N-(p-chlorophenyl)acetamidine 
• 2065-75-0 2-Bromo-malonaldehyde 

Downstream Products

• 1002107-44-9 C₁₁H₉ClF₂N₂ 

Relevant articles and documents

Synthesis and evaluation of new difluoromethyl azoles as antileishmanial agents

Several compounds of great pharmacological interest contain the triazole and imidazole rings. In order to find new drugs with antileishmanial activity we have synthesized and evaluated new imidazole and triazole compounds carrying either the carbaldehyde or the difluoromethylene functionalities against promastigote forms of Leishmania amazonensis. Among the compounds tested difluoromethylene azoles 4b and 8f have inhibited the parasite growth significantly. Our results show that the introduction of the difluoromethylene moieties has turned the inactive carbaldehydes into active antileishmanial compounds.