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3,6-Dihydro-2H-pyran-4-boronic acid is a boronic acid derivative characterized by the molecular formula C5H9BO3. It features a boronic acid group attached to a 2,3-dihydropyran ring, which endows it with unique chemical properties and reactivity. This versatile compound is recognized for its role as a building block in the synthesis of pharmaceuticals and agrochemicals, and it has also been investigated for its potential as a ligand in coordination chemistry. The ability of boronic acids to form reversible covalent bonds with diols makes them valuable in the development of sensors and diagnostics, and their potential as inhibitors in medicinal chemistry, especially in cancer research, has garnered significant interest.

1002127-60-7

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1002127-60-7 Usage

Uses

Used in Pharmaceutical and Agrochemical Synthesis:
3,6-Dihydro-2H-pyran-4-boronic acid is used as a key building block in the synthesis of various pharmaceuticals and agrochemicals. Its unique structure and reactivity allow for the creation of a wide range of bioactive compounds with potential therapeutic and pesticidal properties.
Used in Coordination Chemistry:
In coordination chemistry, 3,6-dihydro-2H-pyran-4-boronic acid is employed as a potential ligand. Its ability to form stable complexes with metal ions makes it a valuable component in the design and synthesis of coordination compounds with specific properties and applications.
Used in Sensor and Diagnostic Development:
3,6-Dihydro-2H-pyran-4-boronic acid is utilized in the development of sensors and diagnostics due to its capacity to form reversible covalent bonds with diols. This property allows for the detection and measurement of various biologically relevant molecules, contributing to advancements in medical diagnostics and environmental monitoring.
Used in Medicinal Chemistry as Inhibitors:
In the field of medicinal chemistry, 3,6-dihydro-2H-pyran-4-boronic acid has been explored as a potential inhibitor, particularly in cancer research. Its ability to target and modulate specific biological pathways makes it a promising candidate for the development of novel therapeutic agents against various types of cancer.
Overall, 3,6-dihydro-2H-pyran-4-boronic acid's diverse applications in organic synthesis, coordination chemistry, and drug development highlight its significance as a versatile and valuable chemical entity.

Check Digit Verification of cas no

The CAS Registry Mumber 1002127-60-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,2,1,2 and 7 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1002127-60:
(9*1)+(8*0)+(7*0)+(6*2)+(5*1)+(4*2)+(3*7)+(2*6)+(1*0)=67
67 % 10 = 7
So 1002127-60-7 is a valid CAS Registry Number.

1002127-60-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name 3,6-dihydro-2H-pyran-4-ylboronic acid

1.2 Other means of identification

Product number -
Other names 3,6-dihydro-2H-pyran-4-boronic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:1002127-60-7 SDS

1002127-60-7Downstream Products

1002127-60-7Relevant articles and documents

Preparation of α-oxygenated ketones by the dioxygenation of alkenyl boronic acids

Patil, Aditi S.,Mo, Dong-Liang,Wang, Heng-Yen,Mueller, Daniel S.,Anderson, Laura L.

supporting information; experimental part, p. 7799 - 7803 (2012/09/08)

Two in two: Dioxygenation of alkenyl boronic acids has been achieved with N-hydroxyphthalimide. The two-step process involves etherification of an alkenyl boronic acid with N-hydroxyphthalimide followed by a [3,3] rearrangement. The dioxygenated product can then be hydrolyzed to form either the corresponding α-hydroxy ketone or the α-benzoyloxy ketone. Copyright

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