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1002243-79-9

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1002243-79-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1002243-79-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,2,2,4 and 3 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1002243-79:
(9*1)+(8*0)+(7*0)+(6*2)+(5*2)+(4*4)+(3*3)+(2*7)+(1*9)=79
79 % 10 = 9
So 1002243-79-9 is a valid CAS Registry Number.

1002243-79-9Downstream Products

1002243-79-9Relevant articles and documents

FGFR Inhibitor compounds and uses thereof

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Paragraph 0359; 0362; 0364-0366, (2021/11/21)

The invention relates to FGFR inhibitor compounds and uses thereof. , The application discloses a compound as shown in a formula (I). A compound, or an optical isomer, a geometric isomer, a tautomer or isomer mixture thereof, or a pharmaceutically acceptable salt thereof, or a prodrug thereof, or a metabolite thereof. The application further relates to the application of the compound in medicine.

(PYRIDIN-2-YL)AMINE DERIVATIVES AS TGF-BETA R1 (ALK5) INHIBITORS FOR THE TREATMENT OF CANCER

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Paragraph 00369, (2020/07/15)

The present invention relates to pharmaceutical compounds, compositions and methods, especially as they are related to compositions and methods for the treatment and/or prevention of a proliferation disorder associated with ΤGFβR1 activity, such as a cancer or fibrosis. The invention provides compounds of Formula (I) and Formula (II) as further described herein having an acidic moiety that enhances tissue specificity for targeted tissues and organs. The invention includes pharmaceutical compositions, pharmaceutical combinations, and methods of use of these compounds for treating conditions including cancer or fibrosis.

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