100230-83-9

Upstream product

• 100231-00-3 (S)-1-(5-Methyl-2-nitro-benzoyl)-pyrrolidine-2-carbonyl chloride 
• 3113-72-2 5-methyl-2-nitrobenzoic acid 
• 100230-79-3 (2S)-N-(5-methyl-2-nitrobenzoyl)proline 
• 100231-00-3 1-(5-Methyl-2-nitro-benzoyl)-pyrrolidine-2-carbonyl chloride 
• 105089-71-2 N-(5-methyl-2-nitrobenzoyl)proline 
• 38818-49-4 5-methyl-2-nitrobenzoyl chloride 

Downstream Products

• 100231-12-7 1,2,3,11a-tetrahydro-7-methyl-5H-pyrrolo<2,1-c><1,4>benzodiazepin-5-one 
• 105089-74-5 11-Hydroxy-7-methyl-1,2,3,10,11,11a-hexahydro-benzo[e]pyrrolo[1,2-a][1,4]diazepin-5-one 
• 100230-91-9 7-Methyl-1,2,3,10,11,11a-hexahydro-benzo[e]pyrrolo[1,2-a][1,4]diazepin-5-one 
• 116564-73-9 7-methyl-11-methoxy-1,2,3,10,11,11a-hexahydro-5H-pyrrolo<2,1-c><1,4>benzodiazepin-5-one 
• 105089-72-3 N-(5-methyl-2-nitrobenzoyl)pyrrolidine-2-carboxaldehyde diethyl thioacetal 
• 105089-73-4 N-(2-amino-5-methylbenzoyl)pyrrolidine-2-carboxaldehyde diethyl thioacetal 

Relevant academic research and scientific papers

A versatile and efficient synthesis of carbinolamine-containing pyrrolo[1,4]benzodiazepines via the cyclization of N-(2-aminobenzoy 1)pyrrolidine-2-carboxaldehyde diethyl thioacetals: Total synthesis of prothracarcin

A versatile and efficient synthesis of carbinolamine-containing pyrrolo[1,4]benzodiazepines (or the corresponding imine forms) of types 2, 7, and 8 is described that involves mercuric chloride mediated cyclization of the corresponding N-(2-aminobenzoyl)py