1002353-89-0

Upstream product

• 5323-87-5 3-Ethoxycyclohex-2-en-1-one 
• 106-96-7 propargyl bromide 
• 504-02-9 1,3-cylohexanedione 

Downstream Products

• 137200-40-9 3-ethoxy-6-<4-(trimethylsilyl)-2-butynyl>-2-cyclohexen-1-one 
• 1010799-02-6 6-(buta-2,3-dienyl)-3-ethoxycyclohex-2-enone 
• 134796-49-9 γ-propynylcyclohexane-1,3-dione 

Relevant academic research and scientific papers

Ring Opening of Cyclopropylketones Induced by Photochemical Electron Transfer

Depending on the substitution pattern of cyclopropylketones, the photochemically induced electron transfer of tertiary amines to cyclopropylketones leads either to the formation of 3-substituted cycloalkanones or to ring expanded products.

Convenient synthesis of (e)-5-aryl(halo)methylenebicyclo-[2.2.2]oct-2-enes and -[2.2.1]hept-2-enes via Lewis acid-promoted carbohalogenation of cyclic 2,6-enynols

An efficient synthesis of (E)-5-aryl(halo)-methylenebicyclo[2.2.2]oct-2-enes is reported. Lewis acid-promoted carbohalogenation of 4-(3-arylprop-2-ynyl)-cyclohex-2-enols in dichloromethane proceeds rapidly to afford the exo-methylenebridged bicycles in good yields. This method also provides an easy access to (E)-5-aryl(halo)methyl-ACHTUNGTRENUNGenebicyclo[2.2.1]hept-2-enes from the five-membered ring 2,6-enynols. The reactions are procedurally simple and high yielding, producing the aryl(halo) methylene-bridged bicycles in minutes under air and mild conditions.

Gold-Catalyzed Cyclizations of Alkynyl Silyl Enol Ethers: An Easy Access to Bicyclo[3.2.1]octanone Derivatives

The efficient gold-catalyzed cyclization reactions of alkynyl silyl enol ethers were successfully applied to the preparation of bicyclo[3.2.1]octanone derivatives. Accordingly, after optimization of the gold catalytic system, several bicyclic α,β-unsaturated keto adducts were synthesized in good to excellent yields. The process followed a major 5-exo cyclization via an anti addition of the silyl enol ether to the π-activated intermediate, which was demonstrated by a deuterium incorporation experiment. A 6-endo cyclization process was observed for a silyl enol ether bearing an electron-donating aromatic group.

A general synthetic route to differentially functionalized angularly and linearly fused [6-7-5] ring systems: A Rh(I)-catalyzed cyclocarbonylation reaction

(Figure Presented) Investigations of a Rh(I)-catalyzed cyclocarbonylation reaction reveal its general synthetic utility for accessing highly functionalized tricyclic [6-7-5] linear and angular ring systems from allene-ynes. Three types of allene-ynes were

Mo(CO)- And [Rh(CO)Cl] catalyzed allenic cyclocarbonylation reactions of alkynones: Efficient access to bicyclic dienediones

Allenyl alkynones are efficiently transformed into fused bicyclic dienediones via cyclocarbonylation reaction conditions. Mo(CO)6/DMSO reaction conditions result in the formation of a bicyclo[3.3.0]octenone ring system, and the [Rh(CO)2/s

C-H amination in synthesis: An approach to the assembly of the B/C/D ring system of aconitine

A strategy for the preparation of aconitine is described that attempts to exploit chemoselective C-H amination and the electrophilic reactivity of oxathiazinane N,O-acetals for assembling the complex, polycyclic carbon framework of the natural product.

A NEW APPROACH FOR THE FORMATION OF FUSED CYCLOOCTANE OR CYCLOHEXANE RINGS

The intramolecular regioselective addition of unsymmetrical allylsilanes to conjugated dienones is shown to permit facile entry into 5-6, 6-6, 5-8, and 6-8 bicyclic ring systems.