1002556-24-2Relevant academic research and scientific papers
New safety-catch photolabile protecting group
Riguet, Emmanuel,Bochet, Christian G.
, p. 5453 - 5456 (2008/09/18)
Photolabile protecting groups have proven their usefulness on many occasions. Their versions as linkers are however less attractive, as robustness and real orthogonality become critical issues. Safety-catch systems, where a preliminary activation phase is necessary, circumvent the problem of premature cleavage. In this work, we introduce a new safety-catch photolabile protecting group, whose cleavage requires the simultaneous presence of light and a chemical promoter.
