100256-18-6Relevant academic research and scientific papers
Cyclopropanation of allylic alcohols using substituted haloalkylzinc reagents: Synthesis of gem-Dimethylcyclopropanes
Charette,Wilb
, p. 176 - 178 (2002)
gem-Dimethylcyclopropanes were obtained by a cyclopropanation of allylic alcohols and ethers using a mixture of diethylzinc and 2,2-diiodopropane in 53-96% yields. Enantioenriched gem-dimethylcyclopropanes were also synthesized using a glucose-derived aux
α7 NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS AND USES THEREOF-I
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Page/Page column 54; 62; 63, (2014/02/16)
The present invention relates to chemical compounds of formula (I), with the substituents as described in the specification, useful in the positive modulation of the alpha 7 nicotinic acetylcholine receptor (α7 nAChR). The invention also relates to the use of these compounds in the treatment or prevention of a broad range of diseases in which the positive modulation of α7 nAChR is advantageous, including neurodegenerative and neuropsychiatric diseases and also neuropathic pain and inflammatory diseases.
