100281-88-7

Upstream product

• 86000-99-9 (R)-(4-Methoxymethyl-cyclohexyl)-((S)-toluene-4-sulfinyl)-acetic acid methyl ester 
• 110928-47-7 (4-Methoxymethyl-cyclohexyl)-methanol 
• 100281-85-4 trans-1-Bromomethyl-4-methoxymethylcyclohexane 
• 1067-74-9 Methyl diethylphosphonoacetate 
• 17159-84-1 4-(methoxymethyl)cyclohexan-1-one 
• 86000-96-6 1-((S)-4-Methoxymethyl-cyclohexylmethanesulfinyl)-4-methyl-benzene 
• 3236-48-4 trans-1,4-Cyclohexanedimethanol 

Downstream Products

• 1114554-27-6 trans (4-Methoxymethyl-cyclohexyl)-acetic acid methyl ester 

Relevant academic research and scientific papers

BENZOYL-PIPERIDINE DERIVATIVES AS DUAL MODULATORS OF THE 5-HT2A AND D3 RECEPTORS

The present invention relates to compounds of formula (I) wherein R1 and A are as defined in the specification as dual modulators of the serotonin 5-HT2a and dopamine D3 receptors, their manufacture, pharmaceutical compositions containing them and their use as medicaments. Compounds of general formula (I) have high affinity for the dopamine D3 and serotonin (5-Hydroxytryptamine; 5-HT) 5-HT2A receptors and are effective in the treatment of psychotic disorders, as well as other diseases such as depression and anxiety, drug dependence, dementias and memory impairment.

DUAL MODULATORS OF 5HT2A AND D3 RECEPTORS

The present invention relates to compounds of the formula (I) wherein R1, R2, X and n are as defined in the specification as dual modulators of the serotonin 5-HT2a and dopamine D3 receptors, their manufacture,