100289-21-2

Basic information

• Product Name: 1-(2-Methyl-iMidazo[1,2-a]pyriMidin-3-yl)-ethanone
• Synonyms: 1-(2-Methyl-iMidazo[1,2-a]pyriMidin-3-yl)-ethanone;1-(2-Methylimidazopyrimidin-3-yl)ethanon
• CAS NO: 100289-21-2
• Molecular Formula: C₉H₉N₃O
• Molecular Weight: 175.18726
• Mol File: 100289-21-2.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(2-Methyl-iMidazo[1,2-a]pyriMidin-3-yl)-ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-Methyl-iMidazo[1,2-a]pyriMidin-3-yl)-ethanone(100289-21-2)
• EPA Substance Registry System: 1-(2-Methyl-iMidazo[1,2-a]pyriMidin-3-yl)-ethanone(100289-21-2)

Safety Data

• Hazardous Substances Data: 100289-21-2(Hazardous Substances Data)

Usage

Class

Skeletal muscle relaxants

Use

Treat musculoskeletal pain and discomfort associated with strains, sprains, and other muscle injuries

Mechanism of Action

Acts on the central nervous system to produce muscle relaxation and relieve pain

Administration

Orally in tablet form

Additional Treatment

May be prescribed in combination with physical therapy and rest

Tolerance

Generally well-tolerated

Common Side Effects

Drowsiness, dizziness, and nausea

Precautions

Avoid consuming alcohol and operating heavy machinery due to potential for increased drowsiness and impaired cognition

Efficacy

Effective and commonly prescribed medication for the relief of acute musculoskeletal pain

Upstream product

• 109-12-6 2-aminopyrimidine 
• 18871-66-4 N,N-dimethylacetamide dimethyl acetal 
• 78-95-5 chloroacetone 
• 123-54-6 acetylacetone 
• 1644540-78-2 (Z)-4-(pyrimidin-2-ylamino)pent-3-en-2-one 
• 1694-29-7 3-chloropentane-2,4-dione 
• 98732-74-2 E-1-Methyl-3-oxo-1-butenylphosphonsaeurediethylester 
• 5049-61-6 2-Aminopyrazine 
• 3043-28-5 3-bromopentane-2,4-dione 

Downstream Products

• 472981-27-4 2-(4-ethoxyphenylamino)-4-(2-methyl-imidazo[1,2-a]pyrimidin-3-yl)thiazole monohydrobromide 

Relevant articles and documents

Therapeutic compounds

The invention provides a compound of formula I: or a salt thereof, wherein R2-R4 and p have any of the values described in the specification, as well as compositions comprising a compound of formula I. The compounds are useful as ant

Hypervalent iodine(III) promoted direct synthesis of imidazo[1,2-a] pyrimidines

An efficient and mild synthesis of imidazo[1,2-a]pyrimidine derivatives has been developed from readily available pyrimidyl arylamines or enamines through a hypervalent iodine-promoted intramolecular C-H bond cycloamination reaction. This protocol allows for the facile construction of biologically active bicyclic imidazo[1,2-a]pyrimidine skeletons as well as other imidazo[1,2-a]-type fused heterocycles.

BMI-1 PROTEIN EXPRESSION MODULATORS

The compounds, pharmaceutical compositions, and methods of using such compounds or compositions thereof described herein are useful for treating a disease modulated by B-cell specific Moloney murine leukemia virus integration site 1 (Bmi-1) protein expression.