100311-54-4

Basic information

• Product Name: 1-(2-nitrophenyl)ethanamine
• Synonyms: 1-(2-nitrophenyl)ethanamine;1-(2-NITROPHENYL)ETHAN-1-AMINE
• CAS NO: 100311-54-4
• Molecular Formula: C₈H₁₀N₂O₂
• Molecular Weight: 166.1772
• Mol File: 100311-54-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 301.4±17.0 °C(Predicted)
• Appearance: /
• Density: 1.199±0.06 g/cm3(Predicted)
• PKA: 7.80±0.10(Predicted)
• CAS DataBase Reference: 1-(2-nitrophenyl)ethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-nitrophenyl)ethanamine(100311-54-4)
• EPA Substance Registry System: 1-(2-nitrophenyl)ethanamine(100311-54-4)

Safety Data

• Hazardous Substances Data: 100311-54-4(Hazardous Substances Data)

Usage

General Description

1-(2-nitrophenyl)ethanamine, also known as 2-Amino-1-nitroethane, is a chemical compound with the molecular formula C8H9NO2. It is a pale yellow solid that is commonly used as an intermediate in the production of pharmaceuticals and organic compounds. It contains a nitro group, which makes it reactive and useful in various chemical reactions. 1-(2-nitrophenyl)ethanamine is generally considered to be a low hazard chemical, and is not known to have any significant health or environmental risks when handled and used in accordance with proper safety precautions and guidelines.

Upstream product

• 288591-69-5 o-nitroacetophenone O-methyl oxime 
• 577-59-3 2-acetylnitrobenzene 
• 1262802-04-9 (E)-1-(2-nitrophenyl)ethanone O-methyl oxime 

Downstream Products

• 204515-43-5 1-[[1-(2-Nitrophenyl)]ethyl]amino]2'-deoxycarbainosine 
• 1431699-56-7 2-Nitro-α-phenethylamine hydrochloride 
• 917222-59-4 acetic acid 2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-{4-[1-(2-nitro-phenyl)-ethylamino]-2-oxo-2H-pyrimidin-1-yl}-tetrahydro-furan-3-yl ester 
• 138571-59-2 N-{(S)-1-[1-(2-Nitro-phenyl)-ethylcarbamoyl]-ethyl}-benzamide 

Relevant articles and documents

A versatile new synthetic route to 1 N-hydroxyindazoles

A new and versatile cyclization reaction affording rare 1 JV-hydroxyindazoles Is presented. Treatment of 2-nitrobenzylamines with methanolic sodium hydroxide furnishes 1 N-hydroxylndazoles regloselectively and In high yield. The reaction tolerates a range

COMPOUND

There is provided a compound having Formula (I), wherein each of R1, R2, R3, R4, R5, R6, R7, R8 and R9 are independently selected from (a) H, (b) R13, -OC(R13)3, -OCH(R13)2, -OCH2R13, -C(R13)3, -CH(R13)2, or -CH2R13 wherein R13 is a halogen; (c) -CN; (d) optionally substituted alkyl, (e) optionally substituted heteroalkyl; (f) optionally substituted aryl; (g) optionally substituted heteroaryl; (h) optionally substituted arylalkyl; (i) optionally substituted heteroarylalkyl; (j) hydroxy; (k) alkoxy; (I) aryloxy; (m) -SO2-alkyl; and (n) -N(R14)C(O)R15, wherein R14 and R15 are independently selected from H and hydrocarbyl, wherein the optional substituents of (d) (e) (T) (h) and (i) are selected from the group consisting of: C1-6 alkyl, halo, cyano, nitro, haloalkyl, hydroxy, C1-6 alkoxy, carboxy, carboxyalkyl, carboxamide, mercapto, amino, alkylamino, dialkylamino, sulfonyl, sulfonamido, aryl and heteroaryl; wherein n and p are independently selected from 0 and 1; X is an optional group selected from O, S, S=O, S(=O)2, C=O, S(=O)2NR16, C=ONR17, NR18, in which R16, R17, and R18 are independently selected from H and hydrocarbyl, R10 is selected from H and hydrocarbyl, R11 is selected from CR19R20 and C=O, in which R19 and R20 are independently selected from H and hydrocarbyl, R12 is selected from a substituted five or six membered carbon rings optionally containing one or more hetero atoms selected from N, S, and O and optionally having fused thereto a further ring, and wherein the one or more substituents are selected from hydrocarbyl groups.