100340-35-0Relevant academic research and scientific papers
Ionic hydrogenation of oxyallyl intermediates: The reductive nazarov cyclization
Giese, S?ren,West
, p. 10221 - 10228 (2007/10/03)
Cyclization of tri- and tetrasubstituted dienones 1 under Lewis acidic conditions in the presence of triethylsilane led to formation of either silyl enol ethers 6 or cyclopentanones 7 in good to excellent yields, depending on work-up conditions. The proposed mechanism involves initial Nazarov cyclization to give oxyallyl intermediates 5, which are intercepted via intermolecular transfer of hydride. The reactions proceeded cleanly with as little as 2 equiv. of silane and in most cases catalytic amounts of Lewis acid could be used. Trapping with Et3SiD occurs at the less substituted terminus in unsymmetrical cases. (C) 2000 Elsevier Science Ltd.
A PALLADIUM-CATALYZED REARRANGEMENT OF 1-VINYL-1-CYCLOBUTANOLS
Clark, Glenn R.,Thiensathit, Sunit
, p. 2503 - 2506 (2007/10/02)
2-Methyl-2-cyclopentene-1-ones are produced by treating 1-vinyl-1-cyclobutanols with bis(benzonitrile)palladium dichloride and benzoquinone in THF.m
