100340-87-2

Basic information

• Product Name: 4-acetylamino-N-hydroxybenzenesulfonamide
• Synonyms: 4-acetylamino-N-hydroxybenzenesulfonamide
• CAS NO: 100340-87-2
• Molecular Weight: 230.244
• Mol File: 100340-87-2.mol
• Article Data: 1

Chemical Properties

• Melting Point: 194-196 °C
• Density: 1.494±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 4-acetylamino-N-hydroxybenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-acetylamino-N-hydroxybenzenesulfonamide(100340-87-2)
• EPA Substance Registry System: 4-acetylamino-N-hydroxybenzenesulfonamide(100340-87-2)

Safety Data

• Hazardous Substances Data: 100340-87-2(Hazardous Substances Data)

Upstream product

• 121-60-8 p-acetylaminobenzenesulfonyl chloride 

Downstream Products

• 21307-20-0 4-Amino-benzol-N-hydroxysulfonamid 

Relevant articles and documents

Piloty's acid derivative with improved nitroxyl-releasing characteristics

Recent studies have shown that nitroxyl (HNO) (1HNO/ 3NO-), which is the one-electron-reduced form of nitric oxide (NO), has unique biological activities, especially in the cardiovascular system, and HNO-releasing agents may have therapeutic potential. Since few HNO donors are available for use under physiological conditions, we synthesized and evaluated a series of Piloty's acid (PA) derivatives and evaluated their HNO-releasing activity under physiological conditions. N-Hydroxy-2- nitrobenzenesulfonamide (17) was the most efficient HNO donor among our synthesized PA derivatives, including the lead compound, 2-bromo-N- hydroxybenzenesulfonamide (2). The high HNO-releasing activity is suggested to be due to electronic and steric effects. Compound 17 may be a useful tool for biological experiments.