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4-acetylamino-N-hydroxybenzenesulfonamide is a chemical compound with the molecular formula C8H10N2O4S. It is an organic compound that belongs to the class of sulfonamides, which are known for their antimicrobial properties. This specific compound features a benzene ring with a sulfonamide group attached to it, and an acetylamino group at the 4-position. The hydroxyl group on the nitrogen atom is responsible for its reactivity and potential applications in various chemical reactions. It is often used in the synthesis of pharmaceuticals and other organic compounds due to its unique structure and reactivity.

100340-87-2

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100340-87-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 100340-87-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,3,4 and 0 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 100340-87:
(8*1)+(7*0)+(6*0)+(5*3)+(4*4)+(3*0)+(2*8)+(1*7)=62
62 % 10 = 2
So 100340-87-2 is a valid CAS Registry Number.

100340-87-2Relevant academic research and scientific papers

Piloty's acid derivative with improved nitroxyl-releasing characteristics

Aizawa, Kazuyuki,Nakagawa, Hidehiko,Matsuo, Kazuya,Kawai, Kodai,Ieda, Naoya,Suzuki, Takayoshi,Miyata, Naoki

, p. 2340 - 2343 (2013)

Recent studies have shown that nitroxyl (HNO) (1HNO/ 3NO-), which is the one-electron-reduced form of nitric oxide (NO), has unique biological activities, especially in the cardiovascular system, and HNO-releasing agents may have therapeutic potential. Since few HNO donors are available for use under physiological conditions, we synthesized and evaluated a series of Piloty's acid (PA) derivatives and evaluated their HNO-releasing activity under physiological conditions. N-Hydroxy-2- nitrobenzenesulfonamide (17) was the most efficient HNO donor among our synthesized PA derivatives, including the lead compound, 2-bromo-N- hydroxybenzenesulfonamide (2). The high HNO-releasing activity is suggested to be due to electronic and steric effects. Compound 17 may be a useful tool for biological experiments.

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