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6-[(E)-2-bromo-2-fluoroethenyl]-2-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione is a complex chemical compound that features a 1,2,4-triazine-3,5(2H,4H)-dione core with two distinct substituents. One is a bromo-fluoroethenyl group, and the other is a deoxy-beta-D-erythro-pentofuranosyl group. 6-[(E)-2-bromo-2-fluoroethenyl]-2-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione is classified as a nucleoside analog, which means it resembles the structure of nucleosides present in DNA and RNA. Its unique structural attributes and properties render it a significant entity in the fields of medicinal chemistry, antiviral and anticancer drug development, and biochemical research for studying interactions between nucleic acids and proteins.

100348-16-1

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100348-16-1 Usage

Uses

Used in Medicinal Chemistry:
6-[(E)-2-bromo-2-fluoroethenyl]-2-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione serves as a key component in the development of antiviral and anticancer drugs. Its structure allows for specific interactions with biological targets, making it a promising candidate for therapeutic applications.
Used in Biochemical Research:
In the realm of biochemical research, 6-[(E)-2-bromo-2-fluoroethenyl]-2-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione is utilized to study the intricate interactions between nucleic acids and proteins. Understanding these interactions is crucial for advancing knowledge in molecular biology and can lead to the discovery of new therapeutic strategies.
Used in Antiviral Drug Development:
6-[(E)-2-bromo-2-fluoroethenyl]-2-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione is employed as a building block in the creation of antiviral agents. Its unique structure enables it to interfere with viral replication processes, offering a potential means to combat viral infections.
Used in Anticancer Drug Development:
6-[(E)-2-bromo-2-fluoroethenyl]-2-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione is also used in the development of anticancer drugs, where it may be designed to target and disrupt specific cellular processes in cancer cells, thereby inhibiting tumor growth and progression.
Used in Pharmaceutical Industry:
6-[(E)-2-bromo-2-fluoroethenyl]-2-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione is used as a pharmaceutical intermediate for the synthesis of various drugs, particularly those with antiviral and anticancer properties, due to its ability to modulate biological activities at the molecular level.

Check Digit Verification of cas no

The CAS Registry Mumber 100348-16-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,3,4 and 8 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 100348-16:
(8*1)+(7*0)+(6*0)+(5*3)+(4*4)+(3*8)+(2*1)+(1*6)=71
71 % 10 = 1
So 100348-16-1 is a valid CAS Registry Number.

100348-16-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name (E)-5-(2-bromo-2-fluorovinyl)-6-aza-2'-deoxyuridine

1.2 Other means of identification

Product number -
Other names 6-((E)-2-Bromo-2-fluoro-vinyl)-2-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-2H-[1,2,4]triazine-3,5-dione

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:100348-16-1 SDS

100348-16-1Downstream Products

100348-16-1Relevant academic research and scientific papers

Synthesis and Antiviral Properties of 5-(2-Substituted vinyl)-6-aza-2'-deoxyuridines

Mitchell, William L.,Ravenscroft, Paul,Hill, Malcolm L.,Knutsen, Lars J.S.,Judkins, Brian D.,et al.

, p. 809 - 816 (2007/10/02)

The following 5-(2-substituted vinyl)-6-aza-2'-deoxyuridines were synthesized: (E)-5-(2-bromovinyl) (2) (6-aza-BVDU), 5-(2-bromo-2-fluorovinyl) (a mixture E and Z isomers) (3), (E)-5-(2-chlorovinyl) (4), (E)-5- (5), 5-(2,2-dibromoviny

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