10035-25-3Relevant academic research and scientific papers
Hydroarylation of bicyclic, unsaturated dicarboximides: access to aryl-substituted, bridged perhydroisoindoles
G?ksu, G?kce,Gül, Melek,?cal, Nüket,Kaufmann, Dieter E.
, p. 2685 - 2688 (2008)
The C-C coupling of the two bicyclic, unsaturated dicarboximides 6 and 8 with aryl and hetaryl halides gave under reductive Heck conditions the 5-substituted N-phenylbicyclo[2.2.1]heptane-2,3-dicarboximides 7 and 9. Reduction of these imides opens a new a
Domino-Heck reactions of carba- and oxabicyclic, unsaturated dicarboximides: Synthesis of aryl-substituted, bridged perhydroisoindole derivatives
Celik, Cumali,Kulu, Irem,Ocal, Nuket,Kaufmann, Dieter E.
, p. 1092 - 1101 (2009)
The C-C coupling of the two bicyclic, unsaturated dicarboximides 5 and 6 with aryl and heteroaryl halides gave, under reductive Heck conditions, the C-aryl-N-phenyl-substituted oxabicyclic imides 7a - c and 8a - c (Scheme 3). Domino-Heck C-C coupling reac
Palladium-Catalyzed [2+1] Cycloadditions Affording Vinylidenecyclopropanes as Precursors of 7-Membered Carbocycles
Lepronier, Aymeric,Achard, Thierry,Giordano, Laurent,Tenaglia, Alphonse,Buono, Gerard,Clavier, Herve
, p. 631 - 642 (2016/02/27)
Palladium(II) acetate in association with secondary phosphine oxides provides an efficient catalytic system for [2+1] cycloadditions starting from oxanorbornene derivatives and tertiary propargyl esters giving rise to vinylidenecyclopropanes. This reaction is specific to bidentate phosphinito-phosphinous acid ligands generated from secondary phosphine oxides. The [2+1] cycloaddition was found broad in scope with a high tolerance to various functional groups. Moreover, vinylidenecyclopropanes were straightforwardly converted into oxabicyclo[3.2.1]oct-2-ene derivatives through a palladium-catalyzed ring-expansion. Finally, the oxa bridge cleavage of oxatricyclic compounds yields functionalized 7-membered carbocycles.
