1003577-32-9Relevant academic research and scientific papers
Synthesis of rare earth catalysts and their applications for enantioselective synthesis of heterocyclic β-amino alcohols
Martin, Myriam,El Hellani, Ahmad,Yang, Jing,Collin, Jacqueline,Bezzenine-Lafollee, Sophie
experimental part, p. 9801 - 9808 (2012/01/13)
A new family of chiral lanthanide complexes derived from (R)-binaphthol has been synthesized by a one-pot procedure using only commercially available substrates. These complexes were evaluated for the aminolysis of meso-epoxides and proved to be efficient enantioselective catalysts. The samarium complex coordinated by two (R)-binaphthoxide ligands was the most enantioselective catalyst of this series. β-Amino alcohols including heterocycles have been isolated with enantiomeric excesses up to 84%.
Insight into the structure of the precatalyst and active species for samarium iodo binaphtholate catalysed aminolysis of epoxides
Martin, Myriam,Bezzenine, Sophie,Collin, Jacqueline
experimental part, p. 1722 - 1729 (2010/10/20)
Samarium iodo binaphtholate is an efficient Lewis acid catalyst for the enantioselective carbon-nitrogen bond formation such as aza-Michael reactions and the aminolysis of epoxides allowing highly enantioenriched aminoalcohols and aminoacids building bloc
