100367-56-4 Usage
General Description
Nicotinonitrile, 1,4-dihydro-4-oxo- (6CI) is a chemical compound categorized under the umbrella of nitriles - a type of organic compound. It contains a nitrile group (-C≡N), which consists of a carbon atom triple-bonded to a nitrogen atom. In its molecular structure, the 1,4-dihydro-4-oxo part refers to the specific arrangement and bonding of atoms within the molecule. The specific properties, uses, and toxicity of Nicotinonitrile, 1,4-dihydro-4-oxo- (6CI) like other chemicals would need to be derived from its Safety Data Sheet (SDS), as these properties can vary widely between different nitriles. Nicotinonitrile, 1,4-dihydro-4-oxo- (6CI) can be used in various industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 100367-56-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,3,6 and 7 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 100367-56:
(8*1)+(7*0)+(6*0)+(5*3)+(4*6)+(3*7)+(2*5)+(1*6)=84
84 % 10 = 4
So 100367-56-4 is a valid CAS Registry Number.
100367-56-4Relevant articles and documents
Optimization of 5-phenyl-3-pyridinecarbonitriles as PKCθ inhibitors
Boschelli, Diane H.,Wang, Daniel,Prashad, Amar S.,Subrath, Joan,Wu, Biqi,Niu, Chuan,Lee, Julie,Yang, Xiaoke,Brennan, Agnes,Chaudhary, Divya
body text, p. 3623 - 3626 (2010/04/26)
The key intermediate, 4-chloro-5-iodo-3-pyridinecarbonitrile, allowed for ready optimization of the PKCθ inhibitory activity of a series of 3-pyridinecarbonitriles. Analog 13b with a 4-methylindol-5-ylamino group at C-4 and a 4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl group at C-5 had an IC50 value of 7.4 nM for the inhibition of PKCθ.
