100367-56-4 Usage
Uses
Nicotinonitrile, 1,4-dihydro-4-oxo(6CI) is used in various industrial applications, although the specific uses are not explicitly mentioned in the provided materials. However, given its classification as a nitrile, it is likely to be employed in the synthesis of other chemicals, pharmaceuticals, or materials that require its unique structural features. The exact applications would be determined by its chemical properties and reactivity, which are outlined in the Safety Data Sheet (SDS) for Nicotinonitrile, 1,4-dihydro-4-oxo- (6CI).
Check Digit Verification of cas no
The CAS Registry Mumber 100367-56-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,3,6 and 7 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 100367-56:
(8*1)+(7*0)+(6*0)+(5*3)+(4*6)+(3*7)+(2*5)+(1*6)=84
84 % 10 = 4
So 100367-56-4 is a valid CAS Registry Number.
100367-56-4Relevant academic research and scientific papers
Optimization of 5-phenyl-3-pyridinecarbonitriles as PKCθ inhibitors
Boschelli, Diane H.,Wang, Daniel,Prashad, Amar S.,Subrath, Joan,Wu, Biqi,Niu, Chuan,Lee, Julie,Yang, Xiaoke,Brennan, Agnes,Chaudhary, Divya
body text, p. 3623 - 3626 (2010/04/26)
The key intermediate, 4-chloro-5-iodo-3-pyridinecarbonitrile, allowed for ready optimization of the PKCθ inhibitory activity of a series of 3-pyridinecarbonitriles. Analog 13b with a 4-methylindol-5-ylamino group at C-4 and a 4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl group at C-5 had an IC50 value of 7.4 nM for the inhibition of PKCθ.
