1003855-50-2Relevant academic research and scientific papers
Synthesis and in vivo antitumor evaluation of 2-methoxyestradiol 3-phosphate, 17-phosphate, and 3,17-diphosphate
Edsall, Allison B.,Agoston, Gregory E.,Treston, Anthony M.,Plum, Stacy M.,McClanahan, Robert H.,Lu, Tian-Sheng,Song, Wei,Cushman, Mark
, p. 6700 - 6705 (2007)
A prodrug strategy was investigated to address the problem of limited aqueous solubility and the resulting limited bioavailability of the antitumor agent 2-methoxyestradiol. The 3-phosphate, 17-phosphate, and 3,17-diphosphate of 2-methoxyestradiol were sy
