Cas 1003877-45-9,C31H36Cl2N4O3

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Check Digit Verification of cas no

The CAS Registry Mumber 1003877-45-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,3,8,7 and 7 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1003877-45:
(9*1)+(8*0)+(7*0)+(6*3)+(5*8)+(4*7)+(3*7)+(2*4)+(1*5)=129
129 % 10 = 9
So 1003877-45-9 is a valid CAS Registry Number.

1003877-45-9Upstream product

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1003877-45-9Relevant academic research and scientific papers

Potent and selective small-molecule human urotensin-II antagonists with improved pharmacokinetic profiles

McAtee, John J.,Dodson, Jason W.,Dowdell, Sarah E.,Erhard, Karl,Girard, Gerald R.,Goodman, Krista B.,Hilfiker, Mark A.,Jin, Jian,Sehon, Clark A.,Sha, Deyou,Shi, Dongchuan,Wang, Feng,Wang, Gren Z.,Wang, Ning,Wang, Yonghui,Viet, Andrew Q.,Yuan, Catherine C.K.,Zhang, Daohua,Aiyar, Nambi V.,Behm, David J.,Carballo, Luz H.,Evans, Christopher A.,Fries, Harvey E.,Nagilla, Rakesh,Roethke, Theresa J.,Xu, Xiaoping,Douglas, Stephen A.,Neeb, Michael J.

scheme or table, p. 3716 - 3719 (2009/04/04)

Lead compound 1 was successfully redesigned to provide compounds with improved pharmacokinetic profiles for this series of human urotensin-II antagonists. Replacement of the 2-pyrrolidinylmethyl-3-phenyl-piperidine core of 1 with a substituted N-methyl-2-

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