1003887-53-3Relevant academic research and scientific papers
A luminescent sensor for tyrosine phosphorylation
Tremblay, Matthew S.,Lee, Minhee,Sames, Dalibor
, p. 5 - 8 (2008/09/17)
We have developed a luminogenic probe for tyrosine phosphorylation based on a short peptide sequence containing an iminodiacetate moiety near the site of phosphorylation. In response to kinase activity, the probe provides a strong luminescence enhancement, resulting from the increased ability of the probe to bind and sensitize Tb3+ and Eu3+ ions upon phosphorylation.
