1004264-53-2Relevant academic research and scientific papers
Semisynthesis, biological activity, and molecular modeling studies of C-ring-modified camptothecins
Samorì, Cristian,Guerrini, Andrea,Varchi, Greta,Fontana, Gabriele,Bombardelli, Ezio,Tinelli, Stella,Beretta, Giovanni Luca,Basili, Serena,Moro, Stefano,Zunino, Franco,Battaglia, Arturo
, p. 1029 - 1039 (2009)
The synthesis, biological activity, and molecular modeling studies of C-ring-modified camptothecins are reported. A general synthetic protocol, based on "C-5 camptothecin (C-5-CPT) enolate chemistry", allows one to obtain various C5-substituted analogues.
CAMPTOTHECIN DERIVATIVES WITH ANTITUMOR ACTIVITY
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Page/Page column 12, (2010/06/11)
Novel camptothecin derivatives having antitumor activity, the processes for the preparation thereof, the use thereof as antitumor drugs and pharmaceutical compositions containing them.
CAMPTOTHECIN DERIVATIVES WITH ANTITUMOR ACTIVITY
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, (2008/06/13)
Novel camptothecin derivatives of Formula (I) having antitumor activity, the processes for the preparation thereof, the use thereof as antitumor drugs and pharmaceutical compositions containing them.
CAMPTOTHECIN DERIVATIVES WITH ANTITUMOR ACTIVITY
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Page/Page column 22-23, (2008/06/13)
5-substituted camptothecin derivatives having antitumor activity, the processes for the preparation thereof, the use thereof as antitumor drugs and pharmaceutical compositions containing them.
