100429-06-9 Usage
Uses
Used in Pharmaceutical Industry:
Dalbavancin is used as an antibiotic for the treatment of acute bacterial skin and skin structure infections, particularly those caused by gram-positive bacteria. Its broad-spectrum activity makes it effective against various pathogens, including methicillin-resistant Staphylococcus aureus (MRSA) and streptococci species. The convenience of its administration, either as a single dose or a two-dose regimen, contributes to improved patient compliance and healthcare efficiency.
Used in Antimicrobial Resistance Management:
Dalbavancin plays a crucial role in managing antimicrobial resistance by providing an effective alternative to conventional antibiotics for the treatment of drug-resistant bacterial infections. Its unique mechanism of action and lipoglycopeptide structure contribute to its efficacy against resistant strains, helping to preserve the effectiveness of existing antibiotics and reduce the emergence of further resistance.
Used in Research and Development:
As a semi-synthetic antibiotic, Dalbavancin serves as a valuable compound for research and development in the field of antimicrobial chemotherapy. Its structure and activity can be further optimized to develop new derivatives with improved properties, such as enhanced potency, selectivity, and pharmacokinetics. Additionally, studies on Dalbavancin can provide insights into the mechanisms of action and resistance of gram-positive bacteria, guiding the development of novel antimicrobial agents.
Used in Combination Therapy:
Dalbavancin can be used in combination with other antibiotics to enhance the treatment of complex bacterial infections. Its broad-spectrum activity and unique mechanism of action can complement the efficacy of other antimicrobial agents, particularly in cases of polymicrobial infections or when facing drug-resistant pathogens. Combination therapy can also help to reduce the likelihood of resistance development and improve treatment outcomes.
Used in Infection Prevention and Control:
Dalbavancin's potent antimicrobial activity and convenient administration make it a valuable tool in infection prevention and control strategies, particularly in healthcare settings. Its use can help to reduce the incidence of healthcare-associated infections caused by gram-positive bacteria, contributing to improved patient safety and reduced healthcare costs. Additionally, Dalbavancin can be incorporated into prophylactic regimens for patients at high risk of developing bacterial infections, such as those with compromised immune systems or undergoing invasive procedures.
Check Digit Verification of cas no
The CAS Registry Mumber 100429-06-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,4,2 and 9 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 100429-06:
(8*1)+(7*0)+(6*0)+(5*4)+(4*2)+(3*9)+(2*0)+(1*6)=69
69 % 10 = 9
So 100429-06-9 is a valid CAS Registry Number.
100429-06-9Relevant academic research and scientific papers
PROCESS FOR PREPARING ISOMERS OF CARMOTEROL
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, (2008/12/07)
A process for preparing a compound of formula (III) comprising condensing an oxiranyl compound of formula (I) with an amine of formula (II) or a salt thereof wherein: R1 is a group selected from alkyl, aryl, allyl, alkoxy, cycloalkyl, heterocyclic, alkenyl, benzocycloalkyl, aralkyl, haloarylalkyl, heteroaralkyl, haloalkyl, alkoxyaralkyl, substituted silyl and benzyl; and R2 is hydrogen, optionally substituted silyl or optionally substituted benzyl. Formula (I), (II) and (III): There is also described a process for preparing (R,R)-carmoterol from compound (III).
Bronchodilating 8-hydroxy-5-{(1R)-1-hydroxy-2-[N-((1R)-2-(p-methoxyphenyl)-1-methylethyl)-amino]ethyl} carbostyril
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, (2008/06/13)
A novel carbostyril derivative of the formula: STR1 or a pharmaceutically acceptable acid addition salt thereof, and a process for preparing same. The compound (I) shows potent bronchodilating activity and is useful as a bronchodilator.
