100449-77-2Relevant academic research and scientific papers
Reductive coupling reactions: A new strategy for C(sp3)-P bond formation
Chen, Zi-Sheng,Zhou, Zhao-Zhao,Hua, Hui-Liang,Duan, Xin-Hua,Luo, Jian-Yi,Wang, Jia,Zhou, Ping-Xin,Liang, Yong-Min
supporting information, p. 1065 - 1068 (2013/02/25)
The C(sp3)-P bond forming reaction utilizing N-tosylhydrazones as readily available alkylating reagents was developed, which provides a new opportunity for preparing phosphine oxide derivatives with moderate to good yields. This reductive coupling reaction is proposed to proceed through an insertion of copper carbene into P-H bond of H-phosphorus oxides. The salient features of the reaction are operational simplicity and functional-group tolerance.
A novel copper-catalyzed reductive coupling of N-tosylhydrazones with H-phosphorus oxides
Wu, Lei,Zhang, Xiao,Chen, Qing-Qing,Zhou, An-Kun
supporting information, p. 7859 - 7862 (2013/06/27)
We report here a novel C(sp3)-P bonds formation via copper-catalyzed reductive coupling of N-tosylhydrazones with H-phosphorus oxides. A variety of aliphatic and aromatic substrates bearing electron-rich and electron-deficient substituents affords phosphine oxide derivatives with moderate to good yields. This work suggests a new transformation of aldehydes/ketones via N-tosylhydrazones to organophosphorus compounds.
