1004538-34-4

Basic information

• Product Name: (R)-tert-butyl 3-aminopyrrolidine-1-carboxylate hydrochloride
• Synonyms: (R)-1-Boc-3-amino-pyrrolidine hydrochloride;(R)-tert-butyl 3-aminopyrrolidine-1-carboxylate hydrochloride;3-Amino-1-pyrrolidinecarboxylic acid tert-butyl ester hydrochloride;(R)-3-AMINO-1-N-BOC-PYRROLIDINE-HCl;(R)-TERT-BUTYL 3-AMINOPYRROLIDINE-1-CARBOXYLATE HCL;(R)-1-(tert-butoxycarbonyl)-3-aminopyrrolidine hydrochloric acid salt
• CAS NO: 1004538-34-4
• Molecular Formula: C9H19ClN2O2
• Molecular Weight: 222.71236
• Mol File: 1004538-34-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: (R)-tert-butyl 3-aminopyrrolidine-1-carboxylate hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-tert-butyl 3-aminopyrrolidine-1-carboxylate hydrochloride(1004538-34-4)
• EPA Substance Registry System: (R)-tert-butyl 3-aminopyrrolidine-1-carboxylate hydrochloride(1004538-34-4)

Safety Data

• Hazardous Substances Data: 1004538-34-4(Hazardous Substances Data)

Usage

General Description

The chemical (R)-tert-butyl 3-aminopyrrolidine-1-carboxylate hydrochloride is a crystalline solid with a molecular formula C11H21N2O2Cl. It is a derivative of the amino acid proline and is commonly used as an intermediate in the synthesis of pharmaceutical compounds. (R)-tert-butyl 3-aminopyrrolidine-1-carboxylate hydrochloride is widely utilized in organic synthesis for the preparation of various bioactive molecules, particularly in the development of pharmaceuticals. The hydrochloride salt form of (R)-tert-butyl 3-aminopyrrolidine-1-carboxylate enhances its solubility and stability, making it more suitable for use in research and pharmaceutical applications.

InChI:InChI=1S/C9H18N2O2.ClH/c1-9(2,3)13-8(12)11-5-4-7(10)6-11;/h7H,4-6,10H2,1-3H3;1H/t7-;/m1./s1

Upstream product

• 147081-49-0 (R)-3-aminopyrrolidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

METHOD FOR PRODUCTION OF OPTICALLY ACTIVE 3-AMINO-NITROGENATED COMPOUND

Aiming at production of an optically active 3-amino nitrogen-containing compound which is useful as an intermediate in synthesis of medicines and pesticides, in particular, an optically active 1-protected-3-aminopyrrolidine derivative, from an inexpensive and readily available raw material by a process which is efficient and can be practiced industrially, an optically active 3-amino nitrogen-containing compound is produced by performing a reaction of an optically active 3-substituted nitrogen-containing compound with ammonia, methylamine, ethylamine or dimethylamine in the presence of water. In addition, a 1-protected-3-aminopyrrolidine derivative is produced by performing a reaction of an optically active 1-protected-3-(sulfonyloxy)pyrrolidine derivative with ammonia, methylamine, ethylamine, or dimethylamine in the presence of methanol, ethanol, n-propanol, or isopropanol under a pressure of less than 30 barr.