100460-06-8

Upstream product

• 60835-69-0 4'-nitrobenzo-15-crown-5 

Downstream Products

• 100460-08-0 Acetic acid 2-(2-{2-[2-(2-acetoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-4-nitro-phenyl ester 
• 100460-09-1 Acetic acid 2-[2-(2-{2-[2-(2-acetoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-4-nitro-phenyl ester 
• 100460-07-9 2-[2-(2-{2-[2-(2-Hydroxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-4-nitro-phenol 
• 100460-10-4 1-Methoxy-2-(2-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-4-nitro-benzene 
• 60835-69-0 4'-nitrobenzo-15-crown-5 
• 53408-96-1 4'-nitrobenzo-18-crown-6 

Relevant academic research and scientific papers

NUCLEOPHILIC RING CLEAVAGE OF CROWN ETHERS, NOVEL METHOD FOR BUILDING UP CROWN ETHER RINGS

The crown ether rings in 4-nitrobenzo-15-crown-5 and -18-crown-6 are cleaved by aqueous alkali affording long chain substituted pyrocatechols which proved to be good starting material for constructing crown ether rings other than the original one.

Benzocrown Derivatives as Ionophores for Alkali Cations, III.- Synthesis of Ring-Cleaved Analogues of Benzocrown Ethers.- A Novel Method for Building Up Crown Ether Rings

Several ring-cleaved analogues (9, 11a,b) of bis(benzo-15-crown-5)-urethanes (1a,b) were prepared to study the change of complexation by electroanalytical methods.The syntheses of the title compounds (9, 11a,b) were accomplished in two ways: starting from 4-nitroveratrole (2) via intermediates 3-8 to give compound 9 and by alkaline hydrolytic cleavage of 4-nitrobenzocrown ethers (10a,b), then by subsequent steps yielding 11a,b.