1004770-08-4Relevant academic research and scientific papers
SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECE
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Page/Page column 31, (2012/02/05)
Compounds of formula (I) and formula (II) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are a
COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR
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Page/Page column 34; 35, (2011/08/04)
Compounds of formula (I) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally usefu
Discovery of α-amidosulfones as potent and selective agonists of CB2: Synthesis, SAR, and pharmacokinetic properties
Marx, Isaac E.,DiMauro, Erin F.,Cheng, Alan,Emkey, Renee,Hitchcock, Stephen A.,Huang, Liyue,Huang, Ming Y.,Human, Jason,Lee, Josie H.,Li, Xingwen,Martin, Matthew W.,White, Ryan D.,Fremeau Jr., Robert T.,Patel, Vinod F.
scheme or table, p. 31 - 35 (2009/04/10)
A series of α-amidosulfones were found to be potent and selective agonists of CB2. The discovery, synthesis, and structure-activity relationships of this series of agonists are reported. In addition, the pharmacokinetic properties of the most p
Compounds Which Modulate The CB2 Receptor
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Page/Page column 11, (2008/06/13)
Compound of formula (I) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful
