100479-70-7

Usage

Explanation

The molecular formula represents the number of atoms of each element present in a molecule. In this case, the compound has 12 carbon atoms, 14 hydrogen atoms, 2 nitrogen atoms, and 1 oxygen atom.

Explanation

The compound is a solid, and its color is described as white to off-white, which means it can range from pure white to a slightly grayish or beige hue.

Explanation

The compound dissolves well in organic solvents, such as alcohols, ethers, and hydrocarbons, which are typically used in chemical reactions and laboratory procedures.

Explanation

The compound's structure consists of an imidazole ring, which is a heterocyclic ring with nitrogen and carbon atoms, and a phenyl group, which is a benzene ring with an attached alcohol functional group.

Explanation

The compound is primarily used in the pharmaceutical industry for the development and production of drugs and medications.

Explanation

As a reagent, the compound can participate in various chemical reactions, such as substitution, addition, or condensation, to form new compounds with different properties and applications.

Appearance

White to off-white powder

Solubility

Soluble in organic solvents

Chemical Structure

Contains an imidazole ring and a phenyl group

Applications

Building block in the synthesis of pharmaceuticals and other organic compounds

Industry

Pharmaceutical industry

Functionality

Can be used as a reagent in organic synthesis

Upstream product

• 10041-06-2 4'-(imidazol-1-yl)acetophenone 
• 288-32-4 1H-imidazole 
• 5391-88-8 1-(4-bromophenyl)ethanol 

Downstream Products

• 239073-32-6 1-(1-chloroethyl)-4-(1H-imidazol-1-yl)benzene 

Relevant academic research and scientific papers

Mechanism-based enzymatic method for reliable determination of absolute configuration of chiral 1-substituted ethanols: Combination with NMR method

It has been demonstrated that lipase is useful not only for kinetic resolution but also for the rapid determination of absolute configurations. We have previously proposed a mechanism represented by transition-state models to rationalize the enantioselect

Pyridine mediated transition-metal-free direct alkylation of anilines using alcohols: via borrowing hydrogen conditions

Herein, we report pyridine and other similar azaaromatics as efficient biomimetic hydrogen shuttles for a transition-metal-free direct N-alkylation of aryl and heteroaryl amines using a variety of benzylic and straight chain alcohols. Mechanistic studies including deuterium labeling and the isolation of dihydro-intermediates of the benzannulated pyridine confirmed the role of pyridine and a borrowing hydrogen process operating in these reactions. In addition, we have extended this methodology for the development of dehydrogenative synthesis of quinolines and indoles, as well as the transfer hydrogenation of ketones. This journal is

RETRACTED ARTICLE: The Manganese(I)-Catalyzed Asymmetric Transfer Hydrogenation of Ketones: Disclosing the Macrocylic Privilege

The bis(carbonyl) manganese(I) complex [Mn(CO)2(1)]Br (2) with a chiral (NH)2P2 macrocyclic ligand (1) catalyzes the asymmetric transfer hydrogenation of polar double bonds with 2-propanol as the hydrogen source. Ketones (43 substrates) are reduced to alcohols in high yields (up to >99 %) and with excellent enantioselectivities (90–99 % ee). A stereochemical model based on attractive CH–π interactions is proposed.

Cheap Cu(I)/hexamethylenetetramine (HMTA) catalytic system for C-N coupling reactions

An efficient C-N coupling reaction of aryl chlorides or bromides with imidazole was successfully performed with cheap and commercially available catalytic system Cu(I)/HMTA. Both aryl bromides and aryl chlorides have been effectively catalyzed by Cu/HMTA, giving products in moderate to good yields. Moreover, aryl halides bearing either electron-withdrawing groups or electron-donating groups could be used in the reaction. Taylor & Francis Group, LLC.