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1,8-Naphthyridine-3-carboxylic acid, 1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4- oxo- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

100490-71-9

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100490-71-9 Usage

Chemical structure

A synthetic compound derived from naphthyridine carboxylic acid with a 2,4-difluorophenyl moiety and a piperazinyl group.

Antineoplastic and antiviral activities

Potential to inhibit the growth of cancer cells and fight against viral infections.

Inhibition of PARPs

May inhibit the enzymatic activity of poly(ADP-ribose) polymerases (PARPs), which are involved in DNA repair processes.

Promotion of PARP dissociation

May promote the dissociation of PARP from DNA, leading to the induction of DNA strand breaks and the disruption of DNA repair processes.

Potential use in cancer treatment

Being studied for its potential use in the treatment of cancer due to its ability to disrupt DNA repair processes and inhibit cancer cell growth.

Potential use in antiviral therapy

Being studied for its potential use in the treatment of viral infections due to its ability to inhibit viral enzyme DNA topoisomerase II and prevent viral replication.

Check Digit Verification of cas no

The CAS Registry Mumber 100490-71-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,4,9 and 0 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 100490-71:
(8*1)+(7*0)+(6*0)+(5*4)+(4*9)+(3*0)+(2*7)+(1*1)=79
79 % 10 = 9
So 100490-71-9 is a valid CAS Registry Number.

100490-71-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2,4-difluorophenyl)-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylic acid

1.2 Other means of identification

Product number -
Other names 1-(2,4-difluorophenyl)-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:100490-71-9 SDS

100490-71-9Upstream product

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