1004996-09-1

Basic information

• Product Name: C₂₄H₃₂O₃Si
• Synonyms: C₂₄H₃₂O₃Si
• CAS NO: 1004996-09-1
• Molecular Weight: 396.602
• Mol File: 1004996-09-1.mol

Chemical Properties

• CAS DataBase Reference: C₂₄H₃₂O₃Si(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₄H₃₂O₃Si(1004996-09-1)
• EPA Substance Registry System: C₂₄H₃₂O₃Si(1004996-09-1)

Safety Data

• Hazardous Substances Data: 1004996-09-1(Hazardous Substances Data)

Upstream product

• 3699-66-9 ethyl 2-diethoxyphosphorylpropionate 
• 118171-02-1 1-(tert-butyldiphenylsilyloxy)-2-propanone 

Downstream Products

• 1004996-14-8 C₂₄H₃₃NO₃Si 
• 1004996-12-6 C₂₄H₃₃NO₃Si 

Relevant articles and documents

Total synthesis of (±)-merrilactone A

The total synthesis of racemic merrilactone A (a neurotrophic agent) is described, featuring simultaneous and stereospecific creation of the C4 and C5 Stereocenters via a notable silyloxyfuran Nazarov cyclization. Full details of the successful synthetic strategy are given, as well as several examples of the interesting reactivity of intermediates that were prepared and studied during the execution of the total synthesis. A detailed investigation of the Lewis acid-catalyzed Nazarov cyclization of silyloxyfurans was conducted, including a systematic study of substrate scope and limitations. In addition, experiments were conducted that suggest the participation of Lewis acidic silicon species in the Nazarov cyclization.