1005179-35-0Relevant articles and documents
Design and structure-activity relationships of potent and selective inhibitors of undecaprenyl pyrophosphate synthase (UPPS): Tetramic, tetronic acids and dihydropyridin-2-ones
Peukert, Stefan,Sun, Yingchuan,Zhang, Rui,Hurley, Brian,Sabio, Mike,Shen, Xiaoyu,Gray, Christen,Dzink-Fox, JoAnn,Tao, Jianshi,Cebula, Regina,Wattanasin, Sompong
, p. 1840 - 1844 (2008/09/19)
Based on a pharmacophore hypothesis substituted tetramic and tetronic acid 3-carboxamides as well as dihydropyridin-2-one-3-carboxamides were investigated as inhibitors of undecaprenyl pyrophosphate synthase (UPPS) for use as novel antimicrobial agents. S