100532-89-6Relevant academic research and scientific papers
Selective isomerization of a terminal olefin catalyzed by a ruthenium complex: The synthesis of indoles through ring-closing metathesis
Arisawa, Mitsuhiro,Terada, Yukiyoshi,Nakagawa, Masako,Nishida, Atsushi
, p. 4732 - 4734 (2002)
Aruthenium complex, generated from the Grubbs carbene catalyst with vinyloxytrimethylsilane, catalyzed the isomerization of terminal alkenes RCH2-CH=CH2 to internal alkenes RCH=CH-CH3. Application of this olefin isomerization to 2-(N-allylamino)styrene gave the corresponding enamines, which were converted into indoles by a standard ring-closing metathesis, see scheme (Ts = tosyl).
