1005350-59-3Relevant articles and documents
Enantioconvergent and Regioselective Synthesis of Allenylsilanes by Nickel-Catalyzed C(sp2)-C(sp3) Cross-Coupling Starting from Racemic α-Silylated Propargylic Bromides
Xu, Yan,Yi, Hong,Oestreich, Martin
supporting information, p. 2194 - 2197 (2021/05/07)
A direct synthesis of enantioenriched allenylsilanes from racemic α-silylated propargylic bromides by an enantioconvergent nickel-catalyzed cross-coupling is reported. The high regioselectivity is governed by the bulky silyl group, and the C(sp2)-C(sp3) bond formation occurs exclusively at the γ-position of the propargyl electrophile. The level of enantioselection induced by a chiral Pybox ligand is moderate.
Enantio-, Regio- and Chemoselective Copper-Catalyzed 1,2-Hydroborylation of Acylsilanes
Nagy, Audric,Collard, Laurent,Indukuri, Kiran,Leyssens, Tom,Riant, Olivier
supporting information, p. 8705 - 8708 (2019/06/13)
Enantioselective synthesis of synthetically significant (α-hydroxyallyl)silanes, (α-hydroxyaryl)silanes, and (α-hydroxyalkyl)silanes is reported. The present copper-catalyzed 1,2-selective hydroborylation of acylsilanes affords the aforementioned products
Synthesis of optically active α-(allenyl)-and a-substituted-α- (allenyl)glycines
Takuya Okada,Oda, Naoko,Suzuki, Hiroyuki,Sakaguchi, Kazuhiko,Ohfune, Yasufumi
supporting information; experimental part, p. 3765 - 3768 (2010/08/22)
The synthesis of various types of optically active α-(allenylsilane- containing)glycines via a chiralitytransferring ester-enolate Claisen rearrangement of α-acyloxy-a-alkynylsilanes is described. The conversion of the rearranged products into the optically active silicon-free α-(allenyl)-and α-substituted-α-(allenyl)glycines was achieved by the removal of the Me2PhSi-or TMS group from the allene terminus.
Au(I)-catalyzed efficient synthesis of α-acyloxy-α′-silyl ketones from α-acyloxy-α-alkynylsilanes
Sakaguchi, Kazuhiko,Okada, Takuya,Shinada, Tetsuro,Ohfune, Yasufumi
, p. 25 - 28 (2008/09/17)
The Au(I)-catalyzed novel conversion of α-acyloxy-α-alkynylsilanes to α-acyloxy-α′-silyl ketones is reported. Ph3PAuOTf in dioxane in the presence of 1 equiv of H2O efficiently catalyzed both the [3,3] sigmatropic rearrangement and a
