1005402-49-2Relevant academic research and scientific papers
Synthesis and structure-activity relationship of 5-pyridazin-3-one phenoxypiperidines as potent, selective histamine H3 receptor inverse agonists
Tao, Ming,Aimone, Lisa D.,Gruner, John A.,Mathiasen, Joanne R.,Huang, Zeqi,Lyons, Jacquelyn,Raddatz, Rita,Hudkins, Robert L.
scheme or table, p. 1073 - 1077 (2012/03/11)
Optimization of the R2 and R6 positions of (5-{4-[3-(R)-2-methylpyrrolin-1-yl-propoxy]phenyl}-2H-pyridazin-3-one) 2a with constrained phenoxypiperidines led to the identification of 5-[4-(cyclobutyl- piperidin-4-yloxy)-phenyl]-6-meth
Pyridizinone derivatives
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Page/Page column 72, (2008/06/13)
The present invention provides compounds of formula (I*): their use as H3 inhibitors, processes for their preparation, and pharmaceutical compositions thereof.
