1005470-57-4Relevant articles and documents
Organocatalytic enantioselective cascade michael-aldol condensation reactions: Efficient assembly of densely functionalized chiral cyclopentenes
Wang, Jian,Li, Hao,Xie, Hexin,Zu, Liansuo,Shen, Xu,Wang, Wei
, p. 9050 - 9053 (2008/09/19)
(Chemical Equation Presented) A cascade of possibility: A novel and highly enantioselective cascade Michael-aldol condensation reaction of α,β-unsaturated aldehydes with dimethyl malonate aldehyde has been developed. The process, efficiently catalyzed by a simple chiral diphenylprolinol TES ether, serves as a powerful approach to the preparation of highly functionalized chiral cyclopentenes with the formation of two new C-C bonds. TES = triethylsilyl.