1005514-86-2

Upstream product

• 50-00-0 formaldehyd 
• 1005514-85-1 3-amino-5-pentafluorosulfanylbenzoic acid 

Downstream Products

• 1005514-87-3 3-dimethylamino-N-methoxy-N-methyl-5-pentafluorosulfanylbenzamide 
• 1005514-88-4 1-(3-dimethylamino-5-pentafluorosulfanylphenyl)ethanone 
• 1005514-89-5 [3-(1,1-dimethoxyethyl)-5-pentafluorosulfanylphenyl]dimethylamine 
• 1005514-90-8 [3-(2-bromo-1,1-dimethoxyethyl)-5-pentafluorosulfanylphenyl]dimethylamine 
• 1005514-91-9 [3-(2-bromo-1,1-dimethoxyethyl)-5-pentafluorosulfanylphenyl]methylamine 
• 1005514-92-0 2-bromo-1-(3-dimethylamino-5-pentafluorosulfanylphenyl)ethanone 
• 1005515-18-3 2-bromo-1-[3-methylamino-5-(pentafluorosulfanyl)phenyl]ethanone 
• 1178584-07-0 N-[3-(2-bromoacetyl)-5-(pentafluorosulfanyl)phenyl]-N-methylacetamide 
• 1180486-31-0 N-[3-[2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydroisoindol-2-yl)acetyl]-5-(pentafluorosulfanyl)phenyl]-N-methylacetamide trifluoroacetate 

Relevant academic research and scientific papers

SF5 DERIVATIVES AS PAR1 INHIBITORS, PRODUCTION THEREOF, AND USE AS MEDICAMENTS

The invention relates to novel compounds of formula I where R1, R2, R3, R4, R5, R9, Ar, Q1, Q2 and Q3 are each as defined below. The compounds of the formula I have antithrombotic activity and inhibit especially protease-activated receptor 1 (PAR1). The invention further relates to a process for preparing the compound of the formula I and to the use thereof as a medicament.

IMINO-IMIDAZO-PYRIDINE DERIVATIVES HAVING ANTITHROMBOTIC ACTIVITY

The invention relates to compounds of the formula I having antithrombotic activity, which in particular inhibit the protease-activated receptor 1 (PAR1), processes for their preparation and use thereof as medicaments.