1005515-06-9

Upstream product

• 1178585-39-1 N-methoxy-N-methyl-5-nitro-3-pentafluorosulfanylbenzamide 
• 1005515-04-7 N-methoxy-N-methyl-3-(pentafluorosulfanyl)-5-(2,2,2-trifluoroacetylamino)benzamide 
• 1005515-03-6 3-amino-N-methoxy-N-methyl-5-pentafluorosulfanylbenzamide 
• 852469-45-5 3-nitro-5-(pentafluoro-λ⁶-sulfanyl)benzoic acid 
• 833-96-5 3-(pentafluoro-λ⁶-sulphanyl)benzoic acid 
• 1005515-05-8 N-(3-acetyl-5-pentafluorosulfanylphenyl)-2,2,2-trifluoroacetamide 

Downstream Products

• 1005514-60-2 2,2,2-trifluoro-N-{3-[2-(3-iminoimidazo[1,5-a]pyridin-2-yl)acetyl]-5-pentafluorosulfanylphenyl}acetamide trifluoroacetate 

Relevant academic research and scientific papers

SF5 DERIVATIVES AS PAR1 INHIBITORS, PRODUCTION THEREOF, AND USE AS MEDICAMENTS

The invention relates to novel compounds of formula I where R1, R2, R3, R4, R5, R9, Ar, Q1, Q2 and Q3 are each as defined below. The compounds of the formula I have antithrombotic activity and inhibit especially protease-activated receptor 1 (PAR1). The invention further relates to a process for preparing the compound of the formula I and to the use thereof as a medicament.

IMINO-IMIDAZO-PYRIDINE DERIVATIVES HAVING ANTITHROMBOTIC ACTIVITY

The invention relates to compounds of the formula I having antithrombotic activity, which in particular inhibit the protease-activated receptor 1 (PAR1), processes for their preparation and use thereof as medicaments.