100557-56-0Relevant articles and documents
6-(3-Carbamoylbicyclohept-2-yl)hexanoic Acids, a New Class of TxA2 Antagonists
Lieb, Folker,Niewoehner, Ulrich,Wendisch, Detlef
, p. 607 - 616 (2007/10/02)
The synthesis of prostanoids 20-27, 40a, b, and 45a, b starting from the educts 1a, b, and 31 is described.Configurational changes concerning to the positions 2 and 3 of the bicyclic system were proofed by 13C-NMR spectroscopy and were also used for the preparation of the four exo/endo derivatives. 25 and 26 are potent TxA2 antagonists.