1005785-45-4 Usage
Uses
Used in Pharmaceutical Industry:
6-Chloroimidazo[1,2-a]pyridin-2-amine is used as a synthetic reagent for the production of various pharmaceutical products. Its unique structural properties allow it to be incorporated into the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
6-Chloroimidazo[1,2-a]pyridin-2-amine is also used as a synthetic reagent in the agrochemical industry. Its incorporation into the development of new agrochemical products can contribute to the creation of more effective and targeted solutions for agricultural challenges.
Safety Precautions:
As with most chemicals, safety precautions are necessary when handling 6-chloroimidazo[1,2-a]pyridin-2-amine. Its potential effects on human health and the environment are yet to be comprehensively studied, so it is essential to follow proper safety guidelines and protocols during its use and disposal.
Check Digit Verification of cas no
The CAS Registry Mumber 1005785-45-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,5,7,8 and 5 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1005785-45:
(9*1)+(8*0)+(7*0)+(6*5)+(5*7)+(4*8)+(3*5)+(2*4)+(1*5)=134
134 % 10 = 4
So 1005785-45-4 is a valid CAS Registry Number.
1005785-45-4Relevant academic research and scientific papers
Zhou, Shiyang,Chen, Guangying,Huang, Gangliang
, p. 503 - 510 (2019)
The Albendazole was used as the lead compound, which was modified by structural transformation and with alkyl groups. A total of 18 compounds (4a–4r) were designed and synthesized. The in vitro experiment results showed that compounds 4e, 4f, 4k, 4l, 4q and 4r had good inhibitory effect on egg and imago of roundworm. IC50 of compound 4l to anti-egg of roundworm was 0.65?±?0.01?μmol/L and to anti-imago of roundworm was 1.04?±?0.01?μmol/L. At the same time, it showed that compound 4l had the best effect in vivo, and the rate of anti-helmintic could reach more than 99%. The results of acute toxicity tests indicated that these compounds were with LD50 > 2100 mg/kg by oral administration, so they were low toxicity compounds. In a word, compound 4l was most likely to be a new anti-helmintic drug through screening in vitro and in vivo.
