1005786-10-6

Basic information

• Product Name: 6-IODOIMIDAZO[1,2-B]PYRIDAZINE-2-CARBOXYLIC ACID ETHYL ESTER
• Synonyms: 6-IODOIMIDAZO[1,2-B]PYRIDAZINE-2-CARBOXYLIC ACID ETHYL ESTER;Ethyl 6-iodoimidazo[1,2-b]pyridazine-2-carboxylate
• CAS NO: 1005786-10-6
• Molecular Formula: C₉H₈IN₃O₂
• Molecular Weight: 317.08319
• Mol File: 1005786-10-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-IODOIMIDAZO[1,2-B]PYRIDAZINE-2-CARBOXYLIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 6-IODOIMIDAZO[1,2-B]PYRIDAZINE-2-CARBOXYLIC ACID ETHYL ESTER(1005786-10-6)
• EPA Substance Registry System: 6-IODOIMIDAZO[1,2-B]PYRIDAZINE-2-CARBOXYLIC ACID ETHYL ESTER(1005786-10-6)

Safety Data

• Hazardous Substances Data: 1005786-10-6(Hazardous Substances Data)

Upstream product

• 70-23-5 ethyl Bromopyruvate 
• 187973-60-0 6-iodopyridazine-3-amine 

Downstream Products

• 1005779-22-5 ethyl 6-(3-aminophenoxy)imidazo[1,2-b]pyridazine-2-carboxylate 
• 1005787-13-2 N-[3-({2-[(cyclopentylcarbonyl)amino]imidazo[1,2-b]pyridazin-6-yl}oxy)phenyl]-3-(trifluoromethyl)benzamide 
• 1005787-07-4 N-[3-({2-[(cyclobutylcarbonyl)amino]imidazo[1,2-b]pyridazin-6-yl}oxy)phenyl]-3-(trifluoromethyl)benzamide 
• 1005785-66-9 N-[3-({2-[(cyclopropylcarbonyl)amino]imidazo[1,2-b]pyridazin-6-yl}oxy)phenyl]-3-(trifluoromethyl)benzamide 
• 1005787-12-1 N-{3-[(2-acetamidoimidazo[1,2-b]pyridazin-6-yl)oxy]phenyl}-3-(trifluoromethyl)benzamide 
• 1005786-94-6 N-(3-{[2-(isobutyrylamino)imidazo[1,2-b]pyridazin-6-yl]oxy}phenyl)-3-(trifluoromethyl)benzamide 
• 1005779-46-3 N-{3-[(2-aminoimidazo[1,2-b]pyridazin-6-yl)oxy]phenyl}-3-(trifluoromethyl)benzamide 
• 1005779-31-6 tert-butyl[6-(3-{[3-(trifluoromethyl)benzoyl]amino}phenoxy)imidazo[1,2-b]-pyridazin-2-yl]carbamate 
• 1005779-28-1 6-(3-{[3-(trifluoromethyl)benzoyl]amino}phenoxy)imidazo[1,2-b]pyridazine-2-carboxylic acid 
• 1005779-25-8 ethyl 6-(3-{[3-(trifluoromethyl)benzoyl]amino}phenoxy)imidazo[1,2-b]pyridazine-2-carboxylate 
• 1005786-92-4 N-(3-{[2-(propionylamino)imidazo[1,2-b]pyridazin-6-yl]oxy}phenyl)-3-(trifluoromethyl)benzamide 
• 1005777-68-3 N-{6-[3-({[3-(trifluoromethyl)phenyl]carbonyl}amino)-phenoxy]imidazo[1,2-b]pyridazin-2-yl}tetrahydro-2H-pyran-4-carboxamide 

Relevant articles and documents

FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF

The present invention provides a fused heterocyclic derivative having a potent kinase inhibitory activity and use thereof. A compound represented by the formula (I): wherein each symbol is as defined in the specification, except a particular compound, or a salt thereof, and a pharmaceutical agent containing the compound or a prodrug thereof, which is a kinase (VEGFR, VEGFR2, PDGFR, Raf) inhibitor, an angiogenesis inhibitor, an agent for the prophylaxis or treatment of cancer, a cancer growth inhibitor or a cancer metastasis suppressor.