100587-68-6Relevant academic research and scientific papers
Topically active carbonic anhydrase inhibitors. 3. Benzofuran- and indole-2-sulfonamides
Graham,Hoffman,Gautheron,Michelson,Scholz,Schwam,Shepard,Smith,Smith,Sondey,Sugrue
, p. 749 - 754 (2007/10/02)
Derivatives of benzofuran- and indole-2-sulfonamide were prepared for evaluation as topically active ocular hypotensive agents. These compounds were found to be excellent inhibitors of carbonic anhydrase and to lower intraocular pressure in a rabbit model
2-Sulfamoyl-1H-indole derivatives for the treatment of elevated intraocular pressure
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, (2008/06/13)
Novel 2-sulfamoyl-1H-indoles and derivatives thereof are shown to be useful for the treatment of elevated intraocular pressure in pharmaceutical compositions designed for systemic or topical ophthalmic administration.
