100595-19-5

Basic information

• Product Name: 2,9-dihydro-3H-indeno[2,1-c]pyridazin-3-one
• CAS NO: 100595-19-5
• Molecular Formula: C₁₁H₈N₂O
• Molecular Weight: 184.194
• Mol File: 100595-19-5.mol
• Article Data: 2

Chemical Properties

• Density: 1.4g/cm³
• Refractive Index: 1.736
• CAS DataBase Reference: 2,9-dihydro-3H-indeno[2,1-c]pyridazin-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2,9-dihydro-3H-indeno[2,1-c]pyridazin-3-one(100595-19-5)
• EPA Substance Registry System: 2,9-dihydro-3H-indeno[2,1-c]pyridazin-3-one(100595-19-5)

Safety Data

• Hazardous Substances Data: 100595-19-5(Hazardous Substances Data)

Usage

Molecular structure

Heterocyclic organic compound with nitrogen and oxygen atoms in its ring structure.

Biological activities

Anti-inflammatory, antioxidant, and antitumor properties.

Therapeutic potential

Suggested for treating various diseases.

Area of study

Medicinal and pharmaceutical chemistry.

Further research needed

To fully understand and harness its potential for medicinal purposes.

Upstream product

• 29983-59-3 2-indanone-1-acetic acid ethyl ester 
• 615-13-4 2-indanone 
• 318472-09-2 2-(2-oxo-indan-1-yl)-2-hydroxyacetic acid 
• 100595-18-4 9H-indeno<2,1-c>-2H-4,4a-dihydropyrazin-3-one 

Downstream Products

• 100595-20-8 3-chloro-9H-indeno<2,1-c>-pyridazine 
• 100595-21-9 9-oxo-indeno<2,1-c>-3(2H)-pyridazinone 
• 100595-17-3 9H-indeno<2,1-c>-pyridazine 

Relevant articles and documents

Synthesis and 'in vitro' antimicrobial properties of N-oxide derivatives based on tricyclic indeno[2,1-c]pyridazine and benzo[f]cinnoline systems

A number of 9H-indeno[2,1-c]pyridazine N-oxides (3a-c) and benzo[f]cinnoline N-oxides (4,5a-c) have been synthesized and tested for antimicrobial activity. All new products were inactive against Gram negative bacteria and fungi. In contrast, among the compounds synthesized, 3b, 4b and 5b showed a moderate activity against Gram positive Staphylococcus aureus and Staphylococcus epidermidis. Of the present series, the 9-nitro-benzo[f]cinnoline N-oxide 5b possessed the highest activity especially against Trichomonas vaginalis (MIC = 3.9 μg/ml).