100622-93-3 Usage
Description
1-(4-Chlorobenzyl)-1H-benzimidazole-2-thiol is a chemical compound belonging to the benzimidazole class, characterized by a thiol group (-SH) and a benzimidazole ring, which is a fused heterocyclic system of benzene and imidazole rings. It also features a chlorobenzyl group, indicating the presence of a chlorine atom attached to a benzyl group, a derivative of toluene. 1-(4-Chlorobenzyl)-1H-benzimidazole-2-thiol may have diverse potential applications, contingent upon the specific context and intended use.
Uses
Used in Pharmaceutical Industry:
1-(4-Chlorobenzyl)-1H-benzimidazole-2-thiol is used as a pharmaceutical intermediate for [application reason]. Its unique structure and properties make it a valuable component in the development of new drugs and therapies.
Used in Organic Synthesis:
In the field of organic synthesis, 1-(4-Chlorobenzyl)-1H-benzimidazole-2-thiol serves as a key compound for [application reason]. Its versatility in chemical reactions allows for the creation of a wide range of derivative compounds with various applications.
Used as a Reagent in Chemical Reactions:
1-(4-Chlorobenzyl)-1H-benzimidazole-2-thiol is utilized as a reagent in chemical reactions for [application reason]. Its presence can facilitate or enhance specific reaction pathways, contributing to the synthesis of desired products.
(Note: The "application reason" should be filled in with specific reasons based on the actual context or intended use of the compound in each industry.)
Check Digit Verification of cas no
The CAS Registry Mumber 100622-93-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,6,2 and 2 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 100622-93:
(8*1)+(7*0)+(6*0)+(5*6)+(4*2)+(3*2)+(2*9)+(1*3)=73
73 % 10 = 3
So 100622-93-3 is a valid CAS Registry Number.
100622-93-3Relevant articles and documents
Synthesis of 2-Alkoxy/Thioalkoxy Benzo[d]imidazoles and 2-Thione Benzo[d]imidazoles via a Phase-Based, Chemoselective Reaction
Yoon, Hyo-Jeong,Yang, Seung-Ju,Gong, Young-Dae
, p. 738 - 747 (2017/12/18)
2-Alkoxy/thioalkoxy benzo-[d]-imidazole and 2-thione benzo-[d]-imidazole libraries were constructed in solution phase and on solid phase, respectively. The key step in this work is the phase-based chemoselective reaction of the 2-mercaptobenzo-[d]-imidazole intermediate with benzyl chloride (solution phase) and Merrifield resin (solid phase). In the solution-phase case, benzyl chloride reacted with the thiol group of 2-mercaptobenzo-[d]-imidazole, whereas in the solid-phase case, Merrifield resin was introduced at an internal amine group of benzo-[d]-imidazole. To afford the desired 2-alkoxy/thioalkoxy benzo-[d]-imidazole analogues, we used various alkyl halides, alcohols, and thiols in solution phase, and to obtain 2-thione benzo-[d]-imidazole derivatives on solid phase, we used diverse alkyl halides and boronic acids. Finally, to measure the drug potential to be orally active and the molecular diversity in three-dimensional (3D) space, we calculated physicochemical properties and displayed energy-minimized 3D structures. As a result, the libraries from solution phase and solid phase show distinct features in physicochemical properties and skeletal diversities in 3D space.