1006299-86-0Relevant academic research and scientific papers
N1-Alkyl pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase
Mitchell, Michael L.,Son, Jong Chan,Guo, Hongyan,Im, Yun-A,Cho, Eun Jung,Wang, Jianhong,Hayes, Jaclyn,Wang, Michael,Paul, Amber,Lansdon, Eric B.,Chen, James M.,Graupe, Doris,Rhodes, Gerry,He, Gong-Xin,Geleziunas, Romas,Xu, Lianhong,Kim, Choung U.
scheme or table, p. 1589 - 1592 (2010/06/19)
A series of N1-alkyl pyrimidinediones were designed, synthesized and evaluated as HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs). Our efforts identified compound 10b, which represents the lead compound in this series with pharmacokinetics
NOVEL HIV REVERSE TRANSCRIPTASE INHIBITORS
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Page/Page column 424; 425, (2009/03/07)
The invention is related to compounds of Formula (I) or a pharmaceutically acceptable salt, solvate, ester, and/ or phosphonate thereof, compositions containing such compounds, and therapeutic methods that include the administration of such compounds.
Novel HIV reverse transcriptase inhibitors
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Page/Page column 30-31; 45-46, (2008/06/13)
The invention is related to compounds of Formula (I), (II), or (III): or a pharmaceutically acceptable salt, solvate, ester, and/or phosphonate thereof, compositions containing such compounds, and therapeutic methods that include the administration of such compounds.
