10063-08-8

Basic information

• Product Name: 17α-amino-5α-androstan-3β-ol
• CAS NO: 10063-08-8
• Molecular Weight: 291.477
• Mol File: 10063-08-8.mol

Chemical Properties

• CAS DataBase Reference: 17α-amino-5α-androstan-3β-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 17α-amino-5α-androstan-3β-ol(10063-08-8)
• EPA Substance Registry System: 17α-amino-5α-androstan-3β-ol(10063-08-8)

Safety Data

• Hazardous Substances Data: 10063-08-8(Hazardous Substances Data)

Upstream product

• 17291-39-3 p-toluenesulfonate of 3β-acetoxy-5α-androstan-17β-ol 
• 1098-12-0 3β-acetoxy-5α-androstan-17-one 
• 5615-34-9 17-hydroxyimino-5α-androstan-3β-ol 
• 77287-34-4 formamide 
• 1600-76-6 3β-acetoxy-5α-androstan-17β-ol 
• 111712-88-0 3β-acetoxy-17β-methylsulfonyloxy-5α-androstane 
• 5615-34-9 (3β,5α)-3-hydroxyandrostan-17-one oxime 

Downstream Products

• 126054-46-4 3β-hydroxy-17α-methoxycarbamoyl-5α-androstane 
• 126054-47-5 3β-methoxycarbonyloxy-17α-methoxycarbamoyl-5α-androstane 

Relevant articles and documents

Steroids, LIII: New Routes to Aminosteroids [1]

Steroid ketoximes were reduced with sodium tetrahydroborate in the presence of nickel chloride or molybdenum trioxide. These processes yielded 17α- and 20α- aminosteroids (1c-5c) in higher yields than common reduction methods.

STEROIDS .LIII. TRANSFORMATION OF 3β-ACETOXY-5α-ANDROSTAN-17-ONE INTO 17α- AND 17β-AMINO DERIVATIVES OF 5α-ANDROSTAN-3β-OL

The epimeric 17α- and 17β-amino-5α-androstan-3β-ols were synthesized from 3β-acetoxy-5α-androstan-17-one.The configurations at the C17 atom were demonstrated by the 1H NMR method.