1006375-89-8Relevant academic research and scientific papers
Vilsmeier reaction of enaminones: Efficient synthesis of halogenated pyridin-2(1H)-ones
Zhang, Rui,Zhang, Dingyuan,Guo, Yongli,Zhou, Guangyuan,Jiang, Zijiang,Dong, Dewen
experimental part, p. 9504 - 9507 (2009/04/06)
(Chemical Equation Presented) A facile and efficient one-pot synthesis of halogenated pyridin-2(1H)-ones from a series of readily available enaminones under Vilsmeier conditions is described, and a mechanism involving sequential halogenation, formylation, and intramolecular nucleophilic cyclization is proposed.
A facile and efficient synthesis of polyfunctionalized pyridin-2(1H)-ones from β-oxo amides under Vilsmeier conditions
Xiang, Dexuan,Wang, Kewei,Liang, Yongjiu,Zhou, Guangyuan,Dong, Dewen
, p. 345 - 348 (2008/09/19)
(Chemical Equation Presented) A facile and efficient one-pot synthesis of polysubstituted pyridin-2(1H)-ones from a variety of β-oxo amides under Vilsmeier conditions is described, and a mechanism involving sequential halogenation, formylation and intramo
